I think it's failing do to the port on SQL server set to something other than default. 

Sound accurate?

dnn version: 04.04.01

Iframe version: 03.02.01

Error: IFrame is currently unavailable.
DotNetNuke.Services.Exceptions.ModuleLoadException: Keyword not supported: 'myserver,1234;database'. ---> System.ArgumentException: Keyword not supported: 'myserver,1234;database'. at System.Data.Common.DbConnectionOptions.ParseInternal(Hashtable parsetable, String connectionString, Boolean buildChain, Hashtable synonyms, Boolean firstKey) at System.Data.Common.DbConnectionOptions..ctor(String connectionString, Hashtable synonyms, Boolean useOdbcRules) at System.Data.SqlClient.SqlConnectionString..ctor(String connectionString) at System.Data.SqlClient.SqlConnectionFactory.CreateConnectionOptions(String connectionString, DbConnectionOptions previous) at System.Data.ProviderBase.DbConnectionFactory.GetConnectionPoolGroup(String connectionString, DbConnectionPoolGroupOptions poolOptions, DbConnectionOptions& userConnectionOptions) at System.Data.SqlClient.SqlConnection.ConnectionString_Set(String value) at System.Data.SqlClient.SqlConnection.set_ConnectionString(String value) at System.Data.SqlClient.SqlConnection..ctor(String connectionString) at Microsoft.ApplicationBlocks.Data.SqlHelperParameterCache.GetSpParameterSet(String connectionString, String spName, Boolean includeReturnValueParameter) at Microsoft.ApplicationBlocks.Data.SqlHelperParameterCache.GetSpParameterSet(String connectionString, String spName) at Microsoft.ApplicationBlocks.Data.SqlHelper.ExecuteReader(String connectionString, String spName, Object[] parameterValues) at DotNetNuke.Modules.IFrame.SqlDataProvider.GetParameters(Int32 ModuleID) at DotNetNuke.Modules.IFrame.IFrame.Page_Load(Object sender, EventArgs e) --- End of inner exception stack trace ---