It's definitely possible, and you might be able to use some of the webfarm support built into DNN. I personally haven't used any of it, I got out of the hardware business long ago, after trying to setup replication and routers and firewalls for running sites out of two different cities. I leave that to the guys who know what they're doing :D

Julian,

I have 2 clients that run DNN in a 'Web Farm' environment. That said, Ido not subscribe to the DNN supported UNC type setup. I use a version of the alternative method explained in the documentation. The reason I do so is to avoid a single point of failure. In the supported model, should the file server go down, you're lights-out until it's brought back online. Replicating files between your web servers assures that each webserver has identical files/data.

However, I have never set-up an "off-site farm", the challanges sound interesting. What are your WAN topology plans?

HTH your decision..