So I have a site that has been up for awhile and i've made changes to everything before also.  When I go to one particular page now, I can't edit any of the modules.  I even added a brand new module and I get the same error.  The page opens okay and shows what it's supposed to.  Everything works except for when I log in and try to edit the modules.  I get the error resource not found.  I don't understand why it wouldn't be there because 1, I've edited it before, and 2, if it wasn't there, why would everything show and work on the page?

Server Error in '/Videos' Application.

---

The resource cannot be found.

Description: HTTP 404. The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable.  Please review the following URL and make sure that it is spelled correctly.

Requested URL: /Videos/tabid/332/ctl/Edit/mid/961/Default.aspx

any ideas as to why this is happening?

Nope.  There's no error anywhere except for the error on the page that I showed above.  And I've restarted IE several times and have tried with several different browsers.  I've even had other users try logging in and trying it and nothing works.

I'm not exactly sure what you mean.  I went into the main DotNetNuke folder in my web server and then opened and saved the web.config file without making any changes to it or anything.  When I open a browser and log in to my site, it still gives me the same error.