Please advice whether this is a DNN issue or not or if anybody have come across that issue and how he/she has handled it.

It has been generated after an ordinary Host -> Restart Application execution.

I'm running DNN 7.3.3 (Build 118)

DomainName UserID 3 UserName 
AssemblyVersion:7.3.3
PortalID:0
PortalName:DomainName.gr
UserID:3
UserName:HostUserName
ActiveTabID:16
ActiveTabName:Host Settings
RawURL:/en-us/Host/Host-Settings/portalid/0
AbsoluteURL:/Default.aspx
AbsoluteURLReferrer: http://DomainName/en-us/Host/Host-Settings/portalid/0
UserAgent:Mozilla/5.0 (Windows NT 5.1) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/38.0.2125.111 Safari/537.36
DefaultDataProvider:DotNetNuke.Data.SqlDataProvider, DotNetNuke
ExceptionGUID:798efaa8-6f88-4ba4-b545-354b5da1022a
InnerException:Value cannot be null. Parameter name: source
FileName:
FileLineNumber:0
FileColumnNumber:0
Method:System.Linq.Enumerable.FirstOrDefault
StackTrace:
Message:
DotNetNuke.Services.Exceptions.PageLoadException: Value cannot be null.
Parameter name: source ---> System.ArgumentNullException: Value cannot be null.
Parameter name: source
at System.Linq.Enumerable.FirstOrDefault[TSource](IEnumerable`1 source, Func`2 predicate)
at DotNetNuke.Services.Installer.Packages.PackageController.GetExtensionPackage(Int32 portalId, Func`2 predicate)
at DotNetNuke.Framework.JavaScriptLibraries.JavaScript.GetScriptVersions()
at DotNetNuke.Framework.JavaScriptLibraries.JavaScript.Register(Page page)
at DotNetNuke.Framework.PageBase.OnPreRender(EventArgs e)
at DotNetNuke.Framework.DefaultPage.OnPreRender(EventArgs evt)
at System.Web.UI.Control.PreRenderRecursiveInternal()
at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
— End of inner exception stack trace —

It happens regularly.

Any feedback to support reproduction.