Just thought i would comment here that you can use both Compression and Whitespace Filtering in DNN 4.4.0.

Change the default Whitespace Filter to a less aggressive expression listed below:

(?<=[>])\s{2,}(?=[<])|(?<=[>])\s{2,}(?= )|(?<= )\s{2,}(?=[<])

And for the Compression, you may need some addiotional entrys to the Exluded Mime Types list. Here is what i have been using below:

image/gif
image/jpeg
image/jpg
image/png
image/bmp
application/zip
application/x-zip-compressed
application/x-gzip-compressed
application/x-compressed
application/octet-stream
application/pdf

I upgraded my DNN 3.3.2 site to 4.4.0 and have been running the Repository Module just fine with those changes.