DNN 4.4.0 (using the install package)
Win XP Pro SP2 (NTFS file system, not FAT or FAT32)
IIS v5.1
SQL Express v9.00.2047.00
ASP.NET v2.0.50727

1. Create a directory and unzip the DotNetNuke install package there. (Mine was C:\DotNetNuke\Website)
2. Create IIS Virtual Directory:
1. Control Panel -> Administrative Tools -> Internet Information Services
2. Open Up the tree: Internet Information Services -> MyComputer (local computer) -> Web Sites
3. Right-click on the MyComputer (default web site) and select New -> Virtual Directory
4. Click "Next"
5. Enter "DotNetNuke" for the Alias and click "Next"
6. Browse to C:\DotNetNuke\Website and click "Next"
7. Check all the following boxes: Read, Run scripts, Execute, Write. 
8. Click "Next"
9. Click Finish
3. Finish configuring DotNetNuke Virtual Directory (right click on the Directory in IIS, "Properties")
1. Virtual Directory Tab
1. Read, Write, Log Visits, Index this Resource.
2. Execute Permissions: Scripts and Executables
3. Application Protection: Medium (Pooled)
2. Directory Security Tab. Left this one alone
3. ASP.NET Tab: Confirm V2.0.5027 is enabled
4. Click "Apply" and "OK"
4. Set up File Access
1. Open Windows Explorer to C:\DotNetNuke\Website and select Tools -> Folder Options
2. Navigate to the “View” tab and clear the checkbox next to “Use Simple File Sharing (Recommended)”
3. Click “Apply to All Folders”
4. Click “OK”
5. Right click on the “Website” folder and select “Properties”
   
6. On the “Security” tab, click “Add”
7. Enter “ASPNET”
8. Click “OK”
9. Check all boxes except “Full Access”
10. Click “Apply”
11. Click “OK”
5. In the web browser, navigate to http://localhost/dotnetnuke.
1.  The database will automatically be created/initialized (this may take some moments)
2. Once the installation has completed click the link at the bottom of the page to access your portal