Hi there,
I just installed the DNN cms yesterday ... took like two days to get it working, however that's because I'm new to MS SQL Server. I've been a php/mysql dev for years. Anyway here's some hopefully helpful information.
My setup:
Windows 2003 Enterprise Server x64
MS SQL Server 2005 Enterprise
IIS 6 w/ ASP.NET 2.0 32-bit. I don't know if ASPx64 will work, but I'm going to give it a shot today. I think it might conflict with 32bit apps from what I've read.
Here's a quick link on how to switch between ASP versions if you don't already know:
support.microsoft.com/kb/894435
Performance:
So far I've encountered no problems, except trying to apply the "vertical-based skin".
SQL is running on the same box (localhost).
When installing I had a problem with the NT Permissions on my virtual folder for the cms.
I ended up having to give users ASPNET and Network Service "Full Control" over the folder, but now that it is installed, I'm going to try reducing all I can. Supposedly All it needs is Read/Write/Execute/Change, but it wouldn't install for me with those set.
I'll keep you posted if you like.
-Danny