Yes this is possible

You would need to create Security Roles (Admin > Security Roles) for each State (say: "[State Name] Administrators"). Then on the state-specific pages, go to Settings (in Page Functions at the top of the page) and give that role the "Edit Page" permission. National Admins can just use the built in Administrators role which gives Edit permission to all pages. Once your roles are set up, just assign the users to the correct Role and you should have the permission levels you want.

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Andrew Nurse
DotNetNuke Core Team Member and Reports Module Project Lead
Microsoft Certified Professional Developer