Well, just wrote my post, clicked 'submit' and got an error, so I'm retyping.  Maybe this is a hint that I should stop considering DNN for my CMS needs. :)

OK, I like DNN a lot.  I've been using it for a couple months, and it's great for building quick sites that non-technical users can maintain.

But, I have a commercial site that I need to build into a CRM system.  My site receives on average 4,000 visits, 50,000 page views and 7GB of data transfer per day.  Per month that's about 120,000 visits, 1,500,000 page views and 200GB of data transfer.

I would believe that given enough hardware, clustering, load balancing, etc, that DNN is capable of serving such a high volume site while maintaining user experience (performance).

My question is, can DNN CE on a well optioned dedicated server handle this type of load?

I won't be paying PowerDNN $1000/month for a hosting setup.  If that's what it takes to serve this type of site, I will find another platform.  However, their entry level dedicated server around $300 is economical.

I'd love to hear from people who have deployed/admin'd a similarly high-volume site on the DNN platform.  Did it work?  Was performance acceptable? 

Anyone have opinions on this?  Looking forward to the responses, thanks!  :)

I run a site with over 10,000 visits a day on a E6850 proc and 4 gigs of ram. The DB server is separate. In fact, it is just one of 8 instances on the box though none of the others have near the traffic. The page loads are good from a server stand point but lose points on the client side due to excessive JS requests and weight.

I recommend reading this guide and installing PageBlaster.