In my email sendig project

When I am using smtp.gmail.com its working fine

when  using my smtp server it shows error  which is:

User not local; please try a different path. The server response was: Sender address is not valid for your login. Check your email program settings.

The code am using is

Dim SmtpMail As New SmtpClient
                    Dim log As New Net.NetworkCredential("mename", "pwd")
                    SmtpMail.Host = ("smtp.myhome.com")
                    SmtpMail.Port = "25"
                    SmtpMail.EnableSsl = False
                    'SmtpMail.UseDefaultCredentials = False
                    SmtpMail.Credentials = log
                    SmtpMail.Send(mEmail)

previously I was used enableSsl as true. that time I got an error "server does not support secure connection "

Now that problem was solved but it remaining. what should i do?

Please help