Accessing the Database and Looking into the Database table on my error in the event Log I have the following:

<ArrayOfAnyType xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><anyType xsi:type="LogDetailInfo"><name>AssemblyVersion</name><value>03.03.05</value></anyType><anyType xsi:type="LogDetailInfo"><name>PortalID</name><value>-1</value></anyType><anyType xsi:type="LogDetailInfo"><name>PortalName</name><value /></anyType><anyType xsi:type="LogDetailInfo"><name>UserID</name><value>-1</value></anyType><anyType xsi:type="LogDetailInfo"><name>UserName</name><value /></anyType><anyType xsi:type="LogDetailInfo"><name>ActiveTabID</name><value>-1</value></anyType><anyType xsi:type="LogDetailInfo"><name>ActiveTabName</name><value /></anyType><anyType xsi:type="LogDetailInfo"><name>RawURL</name><value>/DNN/Default.aspx?error=Object+reference+not+set+to+an+instance+of+an+object.&amp;content=0</value></anyType><anyType xsi:type="LogDetailInfo"><name>AbsoluteURL</name><value>/DNN/Default.aspx</value></anyType><anyType xsi:type="LogDetailInfo"><name>AbsoluteURLReferrer</name><value /></anyType><anyType xsi:type="LogDetailInfo"><name>UserAgent</name><value>Mozilla/4.0 (compatible; MSIE 6.0; Windows NT 5.1; SV1; .NET CLR 1.1.4322; .NET CLR 2.0.50727)</value></anyType><anyType xsi:type="LogDetailInfo"><name>DefaultDataProvider</name><value>DotNetNuke.Data.SqlDataProvider, DotNetNuke.SqlDataProvider</value></anyType><anyType xsi:type="LogDetailInfo"><name>ExceptionGUID</name><value>0ef071e6-0610-4ac3-b213-7abdfbbbd6b7</value></anyType><anyType xsi:type="LogDetailInfo"><name>InnerException</name><value>Object reference not set to an instance of an object.</value></anyType><anyType xsi:type="LogDetailInfo"><name>FileName</name></anyType><anyType xsi:type="LogDetailInfo"><name>FileLineNumber</name><value>0</value></anyType><anyType xsi:type="LogDetailInfo"><name>FileColumnNumber</name><value>0</value></anyType><anyType xsi:type="LogDetailInfo"><name>Method</name><value>N/A - Reflection Permission required</value></anyType><anyType xsi:type="LogDetailInfo"><name>StackTrace</name></anyType><anyType xsi:type="LogDetailInfo"><name>Message</name><value>DotNetNuke.Services.Exceptions.PageLoadException: Object reference not set to an instance of an object. ---&gt; System.NullReferenceException: Object reference not set to an instance of an object.
   at DotNetNuke.Services.Localization.Localization.GetEnabledLocales()
   at DotNetNuke.Framework.PageBase.get_PageCulture()
   at DotNetNuke.Framework.PageBase.OnInit(EventArgs e)
   at System.Web.UI.Control.InitRecursive(Control namingContainer)
   at System.Web.UI.Page.ProcessRequestMain()
   --- End of inner exception stack trace ---</value></anyType><anyType xsi:type="LogDetailInfo"><name>Source</name></anyType></ArrayOfAnyType>

Anybody have any Ideas?

Mike there is a readme file in the documentation folder of the install package it states the following:

Application Upgrades

- make sure you always backup your files/database before upgrading to a new version
- unzip the code over top of your existing application
- BACKUP web.config (web.backup.resources)
- follow procedure in Installation Guide to ensure web.config is set up right
- browse to localhost/DotNetNuke in your web browser
- the application will automatically execute the necessary database scripts

Security ( details in /403-3.htm file )

If using Windows 2000 - IIS5
- the {Server}/ASPNET user account must have Read, Write, and Change Control of the root application directory ( this allows the application to create files/folders )
If using Windows 2003 - IIS6
- the {Server}/NetworkService user account must have Read, Write, and Change Control of the root application directory ( this allows the application to create files/folders )

It it says to unzip the code over top of your existing application if you're going to do this via FTP you need to unzip the application on your local machine and then FTP all the files and do a replace all.  Hopefully you have better results then I did.  If it causes you to have errors you can always restore your old database and copy your old files back over.  Make sure you back everything up and store your backups in a safe location.

Thanks,

-Scott