Thanks Timo!
I read the thread you referenced and it confirmed my thoughts. The error has to be permissions related. So I tried the following:
I reset the permissions for NETWORK_SERVICE to Read, Write, Execute and Delete. After doing this, I tried to open the site in my browser. The site opened without the error. I left the permissions as they were overnight and checked again this morning ~ the site opened without the error. Then, I reset the permissions for NETWORK_SERVICE to Read, Write and Execute and checked the site again ~ no error!
I've been checking the site about every hour and haven't experienced the error yet. Interstingly enough, when I went back and looked at the files that are in the \portals\_default\eventque\ folder, none of the files with names that resemble CLASSID's or GUID-type names remained in the folder. Now I'm wondering if it was an issue that resulted in the original install..... the Delete permission wasn't present for NETWORK_SERVICE, so install couldn't complete its' routine. I didn't experience any error messages throughout the install, but the first time I called the site to complete the set-up, it did throw a runtime error.
So, for the time being, all is well. This might be a way to work-around this type of problem.
Thanks for pointing me in the right direction! If anything changes, I'll post back.
Thanks again!
Matt